Best Probiotics That Work – Compare the Top Probiotic Supplements of 2022

To this day, probiotic supplements have managed to catch the attention of many people globally. Many people have opted for using probiotics to support their digestion, immune system, energy, weight loss, and other essential aspects of health. The one thing that affects every part of your body is the digestive system, and it can be triggered only with good gut bacteria.

Nonetheless, not every gut supplement is the same regarding effectiveness and ingredients. Some supplements contain a strong dose of proven probiotics, while others have almost useless ingredients that might not be healthy.

To make sure you make an educated choice, we’ve tested various probiotic supplements, talked with manufacturers, oversaw lab reports, and spent hours and hours researching today’s most prominent probiotic supplements.

The probiotic supplements that we’ve listed here are of the highest quality, and all of them are backed with scientific evidence of efficiency. Their formula is proven in the industry, and customers have already seen many benefits.

This is what we found.

The Top Probiotic Supplements for 2022

After much research and discussion with professionals, this is how we’ve ranked the best probiotic supplements for 2022:

  • LeanBiome
  • Nucific Bio-X4
  • Seed DS-01
  • JustThrive Probiotic & Antioxidant
  • Live Conscious Pro-45
  • BioFit
  • Organifi Balance
  • BiOptimizers P30m
  • 1MD Complete Probiotics
  • BioTrust Pro-x10
  • ActivatedYou Advanced Restorative Probiotic
  • Gundry MD 24 Strain Probiotic
  • VitaPost Probiotic 40-Billion
  • Probiotic T-50
  • UpWellness Probiotic +
  • Nuzena Probiotic 40 Gut Boost +
  • Probulin
  • Prime Health Daily Probiotic Balance
  • Plurality Health Micelle Liposomal Probiotic
  • Oweli Probiotic
  • Earth Echo Probiotic
  • Microbiome Plus
  • Earth Echo Vitality Bliss Bites
  • FloraSpring (Revival Point)
  • Probiotic America
  • Simple Promise Ovuna
  • Advanced BioNutritionals Advanced Probiotic Formula
  • Organic ProBiotixx
  • Orthobiome
  • ProBio-Lite
  • Vital Plan Biome Boost
  • Vital Plan Advanced Biotic
  • PhytAge Labs Replenish 911



We kick off with one interesting probiotic supplement from Lean For Good. The LeanBiome probiotic supplement is perfect for suppressing hunger, reducing fat storage, and improving metabolism by simply diversifying your gut microbiome.

Recent studies have shown that adding more diversity to your gut health will make it easier to lose some weight. Moreover, with improper gut health, your body will struggle to lose weight, thus becoming harder for the supplement to work on you.

One pill of LeanBiome contains proven and safe ingredients such as Lactobacillus rhamnosus, lactobacillus fermentum, Lactobacillus gasseri, and Greenselect Phytosome to assist you in losing weight and also keep it off from the gut out the rest of the body.

Nucific Bio-X4


The next supplement on our list was formulated to help lose weight. Unlike some other probiotics that function in various ways, the Nucific Bio-X4 is different. The product comes with a 90-day money-back guarantee, but few have ever requested a return.

The Bio-X4 contains four active ingredients to defend you against random cravings, support your digestion, and boost metabolism. With this probiotic supplement, you attack weight loss in many ways with one single shot.

For the Nucific Bio-X4 to provide such benefits, its creators blend proven ingredients such as digestive enzymes, prebiotics, probiotics, green tea extract, and others. The leading weight loss and digestive formulas can optimize digestion in various ways from multiple angles – and this one is a comprehensive formula just for you to combat weight loss.

Seed DS-01


The following reviewed product on the list is Seed DS-01. This is one of the few so-called daily symbiotic supplements in eye-catching packaging. The product features 24 strains of both prebiotics and probiotics, and the supplement is created to support your systemic health while persisting with enzymes, acid, heat, and moisture.

Seed turns to science more than any other probiotic supplement on our list. The creators of Seed formulated this supplement with a single aim in mind – to offer innovative ways of using bacteria to improve biodiversity.

Seed’s DS-01 formula is a high-powered one that supports gastrointestinal health when the entire body wellness supports gut barrier integrity, digestion, cardiovascular health, immune functions, and micronutrient synthesis, among other helpful effects.

JustThrive Probiotic & Antioxidant


The JustThrive Probiotic & Antioxidant is a mixture of spore-based probiotics with many antioxidants for maximum survivability. According to the creators of Just Thrive, the one-of-a-kind delivery mechanism leads to 1000 times better survivability than any Greek yogurt and other leading probiotics on the market.

JustThrive Probiotics contains around 3 billion CFUs of four probiotic strains, including the HU360 and HU58 strains.

According to the manufacturer, you can support your immune, emotional, and digestive health by taking JustThrive probiotics daily.

This probiotic supplement is a safe choice for everyone boasting a paleo, vegan, and keto-friendly formula.

Live Conscious Pro-45


The Pro-45 from Live Conscious is a probiotic formula mixed with fructooligosaccharides or FOS that can boost your probiotic bacteria in various ways.

By taking one pill of Pro-45 daily, you can support optimal digestive and immune health by using over 45 CFUs and 11 robust strains. These dosages of strains can make Live Conscious Pro-45 one of the most potent supplements on this list.

One of the best things about Pro-45 is how it discloses all strains and dosages upfront. Additionally, the product has a high rating of 4.8 out of 5, with over 1000 reviews. This is enough for Pro-45 to be named one of the highest-ranking and best-rated options, and it’s also one of the cheapest.



BioFit is one probiotic supplement that contains a weight loss formula and will cost you no more than $59 per bottle. The formula in question comes with valuable extras that boost the effects of weight loss, including two recipe books for weight loss and access to a private member’s area. This makes BioFit an all-around probiotic supplement when talking about losing weight in various ways.

According to the BioFit official website, some users lost over 723 lbs or even more by taking BioFit regularly. The key is to take BioFit daily as it tends to give your body a consequential dose of probiotic bacteria and then witness tremendous weight loss – all this in a couple of days.

Although some people, including us, are skeptical of overeager weight-loss claims from other people, BioFit is backed with hundreds of positive reviews that support those claims. BioFit Probiotics comes with a 180-day money-back guarantee should you not be pleased with the outcome. If somehow your expectations aren’t met in losing weight, you can ask to be reimbursed.

Organifi Balance


Organifi Balance is one of the few products that is not a capsule but a probiotic formula in powdered form, utilizing only USDA Organic proven components to boost your gut health from different aspects.

With over 20 billion CFUs and five resilient strains per serving, Organifi Balance can improve the diversity of gut flora, improve digestion, and assist you with discomfort and bloating, among other various benefits.

One of the main aspects that we like about Balance from Organifi is its transparency: the company discloses all of the ingredients, probiotic strains, and dosages upfront, making it easy to compare the formula to other formulas that are being sold online today. The other aspect of why we love Organifi Balance is that it contains probiotics in the form of Jerusalem artichoke, which helps you boost the probiotics in your gut after ingestion.

For the reasons mentioned above and many more, Balance from Organifi is one of the best online probiotic supplements.

BiOptimizers P3-OM


The P3-OM from BiOptimizers is one of the top-rated probiotic supplements to increase focus and mental clarity. Furthermore, it can boost energy levels, improve recovery and sleep, reduce gas and bloating, assist you with weight loss, and protect the body against bad bacteria and similar pathogens, among various benefits.

Every pill of P3-OM holds a blend of prebiotic and probiotic components that work to enhance gut health in multiple ways. Probiotic bacteria require the presence of prebiotic bacteria to flourish and persist in the system.

P3-OM from BiOptimizers is made in the US and comes with a 365-day money-back guarantee if you’re not satisfied with the results. Described by some users and reviews as the top-notch probiotic product on the market, the P3-OM is an elite probiotic formula for those that want tremendous results within days.

1MD Complete Probiotics


1MD Complete Probiotics Platinum is a known and trusted probiotic formula with a massive 51 million colony-forming units per serving. This feature alone makes 1MD Complete Probiotic Platinum one of the highest-powered supplements you can find today.

Additionally, 1MD Complete Probiotic Premium is packed with 11 potent strains, boosting your digestion capabilities from various aspects.

The main factor we looked at 1MD is its delivery mechanism: the manufacturer uses delayed-release pills to help the probiotics reach your intestines. Using cheaper probiotics will lose immense probiotics to your stomach acid. With $41 per bottle, 1MD Complete Probiotic Platinum is an excellent choice for all those looking for a highly potent and manifold probiotic supplement.

BioTrust Pro-X10


BioTrust Pro-X10 is a probiotic supplement created to assist you with mood swings, bloating and digestive issues, stress, and other problems that can be rooted in your gut.

By taking BioTrust Pro-X10 daily, you will use various strains to support gut health in many ways. Additionally, with a price set at $34 per bottle, the BioTrust Pro is one of the cheapest probiotic supplements.

According to the formula creators, taking BioTrust Pro daily can help you with weight loss and low energy, even brain fog.

ActivatedYou Advanced Restorative Probiotic


The ActivatedYou’s Restorative Probiotics come with 30 unique strains of probiotic bacteria, allowing you to colonize the system with billions and billions of healthy bacteria to improve comfort and digestive health.

According to the creators of the formula, the Advanced Restorative Probiotic can help you improve your mood, increase energy levels, give you more radiant skin, support the immune system, relieve you from gut issues, and various other benefits.

There isn’t another probiotic supplement on our list that includes the amount of 30 strains. We also value how the designers disclose all 30 strains, making it easy to see how much you’re taking per day.

If you wish to have maximum diversity in your supplement, AdvancedYou’s Restorative Probiotic might be a perfect choice.

Gundry MD 24 Strain Probiotic


The known Gundry MD 24 Strain Probiotic is among the most diverse supplements. The product holds a 4.90 rating on many review sites. Its myriad strain count translates to 30 billion CFUs.

By taking Gundry MD 24, you can ease up bloating and gas, enhance digestive regularity, and maintain a healthy gut, among other various benefits.

Gundry MD 24 Strain Probiotic backs up its consumers with a 90-day money-back guarantee, should you be unsatisfied with the results at the end. The product’s formula is vegetarian, caffeine-free, and dairy-free.

VitaPost Probiotic 40-Billion


The Probiotic 40-Billion from VitaPost can restock your digestive flora to support the immune system’s healthy digestive functions, maintain the level of good bacteria, and improve overall health and wellness.

Each strain incorporated in the supplement was selected for specific benefits and the potential to work in symbiosis with other strains in the combination. With four strains to speak for, the 40-Billion bolsters a strong dose of many strains or, as the name states, 40 billion CFUs per serving for maximum effect.

Those four strains within the probiotic product include Lactobacillus acidophilus, Bifidobacterium lactis, lactobacillus Plantarum, and lactobacillus paracasei. Every single strain works differently to support other effects of the product.

Probiotic T-50


This is one of the high-powered probiotics created by Zenith Labs. Probiotic T-50 supports a balanced gut bacteria ecosystem, tackles the pesky bloating and gas issues, and sustains your healthy immune system, among other perks.

Truth to be told, the Probiotic T-50 is one of the few probiotic supplements on this list that claims to fortify cognitive functions and fortify memory. Studies worldwide have shown that health is essential for cognition, and ignoring it might lead to mental effects – something that should be avoided.

The Probiotic T-50 is packed in east-to-take pills, and it features a specific formula created by a doctor for gut health support. The formula has a positive effect on your gut health in various ways.

UpWellness Probiotic +


Probiotic + from the well-known manufacturer UpWellness is a probiotic supplement created to speed up fat loss, decrease bloating, improve digestion, and boost energy and mood, among other beneficial factors.

Taking the Probiotic + from UpWellness daily gives your body six proven standards of beneficial microorganisms, three herbal superfoods, and a daily dose of fiber, among other ingredients, to battle digestion problems and improve gut health in many ways.

The key to supporting your gut health is not just stacking your body with any probiotic. Besides those above probiotics, your body needs fiber, digestive enzymes, prebiotics, and other helpful ingredients. The UpWellness designers understand the needs better than any other product displayed on this list. Additionally, Probiotic + is physician formulated!

Nuzena Probiotic 40 Gut Boost +


The Probiotic Gut Boost 40+ from Nuzena is known worldwide for its 40 million probiotic bacteria per serving. The product also holds an excellent rating on many review pages, such as this one.

With a $35 per bottle containing 60 veggie capsules, the Nuzena Probiotic Gut Boost is created to increase nutrient absorption, support bloating and inflammation, and enhance digestive health.

Nuzena has designed this probiotic formula with assistance from health professionals, giving its formula a bonus layer of legitimacy over other competing supplements in the industry.

The unique strains included in the Probiotic Gut Boost 40 + can support your gut health in various ways, complementing each other to achieve better and quick results.



Probulin is a known probiotic supplement described as the new generation of probiotic supplements. Probulin features multiple predictions that target different health issues, and Probulin is here to capitalize on the rapidly growing probiotic space.

For example, Some of the products from Probulin claim to support your colon health. Others claim to be created for the immune system and body energy, while the rest are designed for overall care and digestion.

Today, you can purchase Probulin online or in stores. The company is well-known and highly rated and hailed for its wide range of supplements and effects as probiotic products from Probulin are backed with a 45-day money-back guarantee.

Prime Health Daily Probiotic Balance


The Probiotic Balance from Prime Health Daily is an advanced gut-friendly formula that uses DE111 and additional vital components to aid immunity, pounds-shedding, regular defecation, and digestive health.

Like most of the top-notch probiotic products on our list, the Probiotic Balance is presented to people who wish to support their gut health in more than just one way. The unique blend in daily Probiotic Balance contains lactobacillus casei, lactobacillus Plantarum, lactobacillus rhamnosus, etc. These ingredients will help you with losing weight and many other effects.

Where this product excels it’s the price tag. This is one of the cheapest probiotic products on this list, as for $49, you will receive four bottles.

Purality Health Micelle Liposomal Probiotic


Purality Health Micelle Liposomal Probiotic is among the unique & special probiotic supplements on the market for 2022. The star of Purality Health probiotics is not just the micelle liposomal delivery method but its carefully selected centerpiece probiotic strain called L. Rhamnosus. The L. Rhamnosus is one of the most explored and beneficial probiotic ingredients consumed when looking for the digestive system and gut health support.

Formerly known as PuraThrive, the renamed Purality Health company didn’t stop at just that rare formula of probiotic strains but also strived to develop a unique formulation of RcME for maximum absorption of the bacteria. Alongside lactoferrin, the micelle liposome probiotic included in the Plurality Health probiotic supplement will supercharge the bacteria and show optimal results in no time.

This probiotic supplement is delivered by one manufacturer that enjoys an excellent track record. The company has a long history of making superior products that work flawlessly. Due to their unique delivery system, consumers don’t think twice about Purality Health’s probiotic products.

This affordable product is undoubtedly ranked among the top-rated supplements on our prestigious list for 2022.

Oweli Probiotic


The Oweli Probiotic is a supplement that has 40 billion CFUs of probiotic bacteria. The entire formula spectrum has many strains to support your gut wellness and improve response and health in many ways.

Taking the Oweli Probiotics daily will purportedly support weight management, metabolism, skin health, mood and feelings of well-being, and other benefits.

As an extra, for just $30 per bottle, the Oweli Probiotics are gut-busting for a low price, unlike some other expensive products on this list. We also love how Oweli discloses all strains beforehand, including Bifidobacterium lactis, Lactobacillus Plantarum, and others, along with two ingredients. Those ingredients are fructooligosaccharides and marine polysaccharides as prebiotics.

One bottle of Oweli Probiotics contains 60 vegan capsules, and it’s advised to be used daily.

Earth Echo Probiotic


The unique Earth Echo Probiotics features 12 potent strains to boost gut health and immunity, enhance digestion and reduce bloating, among other benefits.

Earth Echo probiotics are one of the few supplements on this list that declares to curb cravings which translates to an optimal balance of the hunger hormones.

To deliver what it’s being advertised, every bottle of Earth Echo Probiotics is packed with 12 strains of probiotic bacteria such as lactobacillus acidophilus, Bifidobacterium lactis, and Lactobacillus Plantarum, among a variety of other vital components.

One bottle of Earth Echo Probiotic features 30 capsules and has 50 billion CFUs, a number you won’t see many times on our list!

Microbiome Plus


Microbiome Plus is a probiotic supplement that proclaims to elevate the quality of digestive and immune health by using a variety of supplements, strains, and other products.

The company’s primary creation incorporates a unique type of probiotic called L. Reuteri NCIMB 302424, and it’s clinically proven for its effectiveness. According to statements from the manufacturer, the unique strain will lower LDL cholesterol by 11.60%, improve gastrointestinal health, and boost vitamin D by a good 25%, among various other benefits.

If you’re someone that appreciates a potent supplement or a mixture of both probiotics and prebiotics, then look no further than Microbiome Plus since it’ll check all the right boxes for you.

The product is a collection of ingredients that you can use to enhance gut health in multiple ways.

Earth Echo Vitality Bliss Bites


Have you ever thought of enjoying probiotics while eating, let’s say, chocolate? Well, this is now possible. The second Earth Echo supplement on our list offers just that. The Earth Echo Vitality Bliss Bites can have probiotics with chocolate flavor. One of the best options here is the 72% cacao one, and the delicious bites contain probiotics and prebiotic ingredients to enhance your gut health – while eating chocolate!

The chocolate used to produce these bites is USDA Organic attested and ethically sourced. The product is guilt-free and supports your gut health without capsules, tablets, or powder found in other supplements of this kind.

The Vitality Chocolate Bliss Bites are also made of coconut sugar and organic agave inulin as a flavoring agent. Instead of filling your body with artificial sweeteners and compounds, this probiotic supplement emphasizes natural components for better gut health results.

FloraSpring (Revival Point)


The famous probiotic supplement from Revival Point, FloraSpring, claims to decrease calorie absorption, making it easier to lose weight.

Usually, when you eat any food, the body absorbs all or majority of the calories from that food. Yet, when you intake FloraSpring daily, its formula starts to work by reducing the absorption of calories, enabling you to intake a smaller amount of calories to begin shedding pounds quickly and without much effort.

The other advertised advantages of FloraSpring include support of focus and energy, reduced hunger cravings, and

metabolism. There are various other benefits, but you already know the main ones!

Probiotic America Perfect Biotics


Probiotic America is a probiotic supplement in the lineup of Dr. Cary Nelson. This probiotic supplement is here to optimize gut health in many ways. This product makes the company a well-known brand in the US, mainly because the supplement mixes more than 12 probiotic strains and 30 billion CFUs to improve your gut health significantly.

To create Probiotic America, researchers and developers have tested numerous combinations of beneficial bacteria that will deliver a powerful effect. The manufacturer was designed to improve your life and the health of everyone on Earth.

Our bodies host over 100 trillion bacterial cells, which supersedes the number of human cells by 10 to 1. With the consumption of Probiotic America’s Perfect Biotics, you’ll enable your gut system to perform its best.

Simple Promise Ovuna


Ovuna from Simple Premise is a probiotic supplement created to relieve symptoms of menopause, enhance weight management, and aid your overall gut health, among other benefits.

While other probiotic products on our list are helpful for digestion and weight loss, Ovuna is one of the few designed probiotic supplements that can relieve your symptoms of menopause.

Simple Promises’ Ovuna contains ingredients that you might not see in other products on this list. This probiotic supplement contains L. gasseri, B.breve, and B.Lactis. The additional elements are moringa oleifera, curry leaf, turmeric, and other less known but valuable ingredients.

Ovuna contains 15 billion CFUs per serving and high-powered probiotics underneath all of the ingredients above.

Advanced BioNutritionals Advanced Probiotic Formula


The Advanced Probiotics Formula from Advanced BioNutritionals is one of the less pricy supplements we’ve reviewed that enjoys an admirable track record. One bottle costs $20, but don’t let the price trick you – it is cheap, but it’s also very effective.

The high-valued potency formula includes four strains to support memory, cognition, digestion, and whole-body health. Each capsule holds a powerful quantity of Lactobacillus acidophilus, Bifidobacterium bifidum, and Bifidobacterium longum, among various others.

As an extra, the supplement also boasts 15 billion CFUs within the four strains. It also includes a healthy dose of fructooligosaccharides as a prebiotic. With this, you can support digestion and gut health in many ways – and all of this for just $20!

Organixx ProBiotixx


The Probiotic formula from Organixx claims that it can rapidly relieve issues with your digestive problems, such as belly bloat and constipation.

By taking ProBiotics once per day, you will feel increased focus mental clarity, get more energy, relieve bloating and gas, and you can lose from 5 to 10 lbs and even more – an all-in-one probiotic supplement with tons of other benefits.

Every capsule of ProBiotixx has 2.5 billion CFUs, which is an excellent advantage per pill. While other probiotics deliver tons of strains, ProBiotixx focuses on providing a single and potent dose of just one strain: Lactobacillus Plantarum, one of the most known & effective probiotics strains.



This is one of the few doctor-formulated probiotic supplements on our list. The Healthy Living Association creates it, and it’s a bottle that contains 60 capsules.

It boasts 20 billion CFUs, spread across nine probiotic strains. Orthobiome is a highly potent probiotic that declares to get rid of bloating and gas, clear away the mental fog, lessen the mood and anxiety swings, and assist you with weight loss and other prominent advantages.

Orthobiome can assist you with weight loss by reducing your craving for junk food and sugary foods. This makes it easier for you to handle your weight, control your appetite, and speed up stomach fat loss. For just $30 for one bottle, Orthobiome can be ranked as one of our list’s cheapest yet most effective probiotic products.



Now, we’re going to switch from probiotic supplements that everyone can use. The following product on our list, ProBio-Lite, is intended for seniors who look to offer their gut health some much-needed support.

As you grow older, you will need different additional nutrients to support your everyday functions. ProBio-Lite encompasses 5 billion CFUs of probiotic bacteria that will assist your digestive system to function correctly. Additionally, ProBio-Lite helps you reduce heartburn and can improve your overall digestion and gut health.

The product contains a mixture of popular and known gut health-boosting ingredients such as Lactobacillus acidophilus, lactobacillus salivarius, and Bifidobacterium lactis, among others known ingredients to accomplish all of the benefits mentioned above.

Vital Plan Biome Boost


Vital Plan’s Biome Boost is a probiotic supplement created by Dr. Bill Rawls to sustain your gut health in several aspects. The formula mixture has five ancient herbs to help you manage microbes in the gut.

The Biome Boost is one of the few probiotic supplements on this list that comes only in liquid form, as all others are either capsules or powder. The daily take is two droppers per day as it is, or by mixing it with water.

Each product serving contains 1,920mg of ingredients that you don’t see in other products. This includes Cryptolepis sanguinolenta root extract, houttuynia cordata plant extract, Chinese salvia root extract, and neem leaf extract, among various others. Together, these mixed ingredients can tackle gut health in many unique ways.

Vital Plan Advanced Biotic


This is the second probiotic supplement from Vital Plan. Unlike the first one, this one comes in the form of capsules. The Advanced Biotic from Vital Plan comes with six-time-tested herbs that support immune functions and health.

Advanced Biotics comes at $58 a bottle, offering a 90-day money-back guarantee if you haven’t seen any results. Every capsule comes with ingredients like cat’s claw extract, Japanese knotweed extract, sarsaparilla, and berberine, among other helpful elements.

Advanced Biotics is the only supplement on this list that technically doesn’t contain probiotics – weird, right? Instead of that, Vital Plan Advanced Biotics supports probiotics already present in your digestive tract.

The unique blend of extracts can support gut function and probiotics in many ways.

PhytAge Labs Replenish 911


The last item on our list is the Replenish 911 from PhytAge Labs. This is a high-powered probiotic supplement backed by a good marketing campaign.

According to the creator of Replenish 911, the product contains ten probiotic strains to assist your gut health in many ways. Namely, one of the strains in this supplement can help you shed anywhere from 10lbs to 34lbs in close to a month.

Besides the dramatic weight loss claims, Replenish 911 can slow stomach bloating, exhibit antioxidant effects, and control inflammation, among other helpful benefits. Although we might be skeptical of the considerable weight loss in just four weeks, the Replenish 911 is still among popular gut health supplements today.

Our Criteria for Ranking the Best Probiotic Supplements

It’s not a secret that every probiotic product on our list claims that it is the best one. When supporting your gut health, you can’t be too careful with which supplement you feed to your body. Unfortunately, if you look from the ‘other side of things, there are significant differences between each product, requiring a unique approach.

This is how we managed to separate the best and the worst products from our list:

Quality and Strain Diversity

There are hundreds of essential probiotic strains. Each of the strains is associated with different outcomes. The best supplements use multiple strains to balance gut health in more than one way. To maximize gut health, you’ll need as many strains of quality probiotic supplements as possible and nothing under that.

Additional Ingredients

We talk about ingredients like prebiotics and digestive enzymes when speaking about additional components. We all know that probiotics are critical for our gut health, but they can’t function alone. They need extra ‘fuel’ to thrive and survive. Prebiotics are a particular kind of fiber that supports the incidence of gut bacteria and boosts overall gut health. There are products on our list that include the optimal mix of prebiotics, probiotics, and digestive enzymes to battle gut health in various manners.

Price and Value

This is one of our most important criteria when choosing the best probiotic supplements. First of all, you don’t have to break the bank while purchasing a probiotic supplement. There are adequate & effective supplements ranging from $20 to $50 and will most definitely have the same effects as the expensive ones. Some manufacturers can charge a premium price for ‘special’ ingredients, while the rest can charge the exact high cost for no reason at all.

Money-Back Guarantee

It’s not a secret that some probiotic supplements won’t work on you. In other words, they won’t bring out the results you’ve been expecting, or they don’t provide the targeted benefits. In this case, most of the products listed here are subject to money-back guarantees. We considered those probiotic supplements that supported their declarations with a satisfaction guarantee. The most favored probiotic products offer a 60 to a 90-day money-back guarantee, but some offer a 365-day guarantee for the whole year.

Delivery System

Some probiotic manufacturers are known to film-coat the pills to protect all active ingredients as they are transported into your system, safe from stomach acid. All probiotic products contain living bacteria. Without the correct remedy, your stomach can destroy that bacteria before reaching your gut. A smaller probiotic with a sound delivery system can be better than a larger probiotic pill with weaker effectiveness.

Colony Forming Units (CFU)

This is our most important criterion of all. The more abundant CFUs the probiotic is, the more living cultures colonize the digestive tract. Unfortunately, the higher CFUs don’t always mean that a particular product is excellent and effective. CFUs are one of many indicators that we use to rank every probiotic supplement available on the market today. Before you decide which one to take from our list, check the amount of CFUs – it’s must-know information for all potential buyers.

Advertised Benefits & Weight Loss Claims

Some supplement manufacturers have ridiculous claims. For instance, some say that their product can help you lose 30lbs in a month without any diet whatsoever. This is known as dishonest marketing, just to trick you into buying their product. The truth is that no such probiotic product can help you with such weight loss in just 30 days or so. Our list contains only manufacturers with reasonable marketing claims and offers nothing but the truth about their products.

Manufacturer’s Reputation & Transparency

Like any market today, well-established manufacturers have made quality products, thus having more experience than others. On the other side, there have been many new probiotic supplement designers that are launching new formulas. They are doing their best to profit from recent trends and make a global market breakthrough. We aren’t going against these new manufacturers, but we always prefer designs with better products, for obvious reasons.

Formulated by Nutritionists, Dietitians, and Doctors

The world’s best probiotic supplements are made by PhDs, medical doctors, registered nutritionists, dietitians, and other recognized professionals. We avoided supplements designed by marketing members or stole known formulas from previous products.

What Are Probiotics?

If you didn’t know, probiotics are beneficial bacteria present in your digestive tract.

Although you might not want to know this fact, the human body hosts more than ten times more bacterial cells than human cells. The bacterial cells perform vital functions throughout the entire body.

Although probiotic supplements have caught the attention of a broader audience in recent years, they have been around for quite a time. For example, Northern Europeans end up with probiotics-packed systems simply because of their dieting practices – consuming fermented foods, like yogurt. Probiotic beverages have also been popular in the land of the rising sun, Japan.

Since the mid-90s, probiotic supplements have grown in popularity. The increasing research since the old days has connected probiotics to various benefits.

More than 100 trillion microorganisms spread across 500 strains inside your bowels. By complementing the bacterial strains and colonies with any probiotic supplement, you may experience benefits.

The 12 Best Benefits of Probiotics

According to many experts, including ones from Harvard Health, probiotic supplements may affect your health in several aspects, including these beneficial properties:

Balance Friendly Bacteria in the Digestive System

The digestive system breaks down the food you consume, extracts its nutrients, and performs a vital role in your health and wellness. By taking probiotic supplements, you assist the balance of the friendly bacteria within your gut.

Fight Diarrhea

If you have problems with diarrhea, consider taking a probiotic supplement of any kind. According to one study, researchers found that probiotic supplements can reduce antibiotic-associated diarrhea by around 42%!

Support Cholesterol

If you didn’t know, gut health is associated with cardiovascular health. Gut health impacts cholesterol by blocking the body from absorbing ‘bad’ cholesterol while absorbing the ‘good’ one. In many studies, researchers have found specific probiotic bacteria that reduce cholesterol by breaking the bile in the gut, thus aiding digestion in the process.

Regulate Blood Pressure

Some studies have associated probiotics with blood pressure. In a recent review of nine studies, researchers discovered that probiotic supplementation had been associated with low blood pressure. Unfortunately, this doesn’t mean that all probiotic supplements will have the same blood pressure effects.

Enhance Immunity

Around 80% of the immune system is located in the gut. The gut plays a vital role in filtering toxins, defending the body, and supporting the gut lining. In a recent study, it was found that probiotic supplements can help you boost your immune system. Furthermore, having healthy bacteria levels seems to be associated with low-risk respiratory infections.

Promote Weight Loss

In recent years, many people have started taking probiotics to lose weight. Studies have shown that probiotic supplements can help you feel ‘full’ and boost your appetite control, so you won’t have to eat every 20 minutes. Some other studies have shown that probiotic supplements can block the body from absorbing excessive amounts of fat, thus letting you absorb a lower amount of calories from the food you’ve eaten.

Now, don’t take this for granted. Not all supplements that are listed above can help you lose weight. Furthermore, the listed supplements can assist you in losing a small portion of the weight, but all of it. The supplements exist to help your gut in multiple ways but are not created to lose weight entirely. This works on some consumers, but not every single one.

Help with Inflammation

For multiple reasons, your gut can become inflamed. The inflamed gut is connected to an increased risk of disease and can lead to diarrhea, irritable bowel syndrome, and even Crohn’s disease. By taking probiotics, you can support healthy inflammation in the gut and throughout the whole body, assisting it to control the risk of illness.

Alleviate Irritable Bowel Syndrome Effects

If you experience irritable bowel syndrome, taking probiotics might help. Many consumers report experiencing lesser symptoms of irritable bowel syndrome after taking a few probiotic supplements. Irritable bowel syndrome can be linked with gut inflammation, so supplements can greatly assist.

Support Gut Health & Digestion

The sole reason why probiotics exist is to help you with overall gut health and digestion. A good supplement will support both gut health and digestion by raising the levels of the helpful bacteria in your digestive tract.

Aid with Eczema and Allergies

Many consumers have reported that they’ve found some relief from their eczema and allergies by taking probiotics. Although this is not entirely proven by studies worldwide, there have been some ‘small’ results that confirm these claims. These studies have presented a connection between probiotics during allergies and infancy. According to the study, infants fed probiotics-supplemented milk proclaimed a lower incidence of eczema than milk without probiotics.

On the other hand, other studies suggest that women who take supplements during pregnancy can pass between eczema and allergy defense to their baby once born.

Sustain Cognition, Memory, and Clear Mental Fog

Some people are surprised to find their metal fog disappearing after taking a probiotic. This means that your cognition is, you guessed it, linked to your gut. Then the gut bacteria are imbalanced, and the gut will send confusing signals to the brain. A good probiotic supplement can assist you with cognition, mental fog, memory, and overall brain support.

Promote Urological & Vaginal Health

Some consumers use probiotic supplements for vaginal and urological health. Probiotics can further enhance the properties of the bacteria and provide a healthy microbiome. A good supplement can restore microflora balance in the urological tract and vagina, thus helping with yeast infections, bacterial vaginosis, and urinary tract infections.

Recommended Dosages

Each probiotic supplement has a different CFU and strains, and there is no ‘ideal’ recommended dosage for taking. To be considered a probiotic, yogurt, for example, must contain at least 1 billion CFUs of bacteria.

Most supplements on the market today have around 5-10 billion CFUs. On the other hand, the most powerful ones have about 50-100 billion CFUs per serving – that’s a lot, isn’t it?

Side Effects

First, side effects are not associated with significant effects when adults use standard dosages. Considering the review published by the National Institute of Health, probiotic supplements have been proven safe for use in many cases.

However, some consumers have experienced gas, abdominal discomfort, mild bloating, or constipation during the first few days. On the other hand, most consumers have experienced nothing of the sort.

Scientific Evidence

There is tons of scientific evidence today that proves the efficiency & safety of supplements. Studies show taking supplements can assist your digestive health, boost immunity, and help you with weight loss, among various other benefits.

In recent reviews by the National Institute of Health, scientists for probiotic strains such as Saccharomyces boulardii being associated with the following effects:

  • Help you with colic in infants
  • Assist you in supporting your body’s defense against asthma, allergies, and acne
  • Produce substances that can create a desirable effect on the digestive tract
  • Help maintain a healthy connection of microorganisms
  • Influence the body’s immunity and boost the immune system as a whole
  • Supports gut health for specific digestive conditions such as inflammatory bowel disease, constipation, diarrhea, and bowel disease

Although probiotics are already present in your gut, they affect the entire body. The gut holds around 80% of your immune system, and it’s this system that influences all corners of your body. When supporting gut health with a supplement, you also help the body’s defense in various ways.

Researchers found supplements in one Harvard Health review that can effectively prevent or treat irritable bowel syndrome, lucrative colitis, Crohn’s disease, H.pylori, vaginal infections, diarrhea, and other problematic issues.

However, the researchers from Harvard also discovered that similar strains of probiotics might have vastly different results. Taking one probiotic supplement strain won’t lead to all the benefits listed above. Some strains deliver a more powerful effect, while others can only contribute to bettering certain areas in the body.

By choosing the perfect supplement, you can increase your chances of experiencing all other benefits.

Other people take probiotics to battle diarrhea. Multiple studies have shown that probiotics can affect how prolonged diarrhea lasts. In similar studies, probiotics can also reduce the incidence of diarrhea even if it’s not conditioned by a specific condition or disease, reducing it by 42%. Other studies have shown a lowered risk of diarrhea for 57% in children and about 26% in adults, making some probiotic supplements idle for some users.

Evidence suggests probiotics are linked to cognition, mental fog, mental health, and memory. In one review of around 15 studies on these supplements, scientists found that probiotics can improve OCD, memory, depression, autism, and anxiety. Those that participated in this research were tested for one to two months and experienced significant cognitive effects.

Probiotics can generally help you lose weight, which is one of the main reasons consumers use them. Because of its various function mechanisms, researchers found that probiotic supplements can help you lose weight to certain levels. Some supplement strains block the absorption of fat in the intestines, while others can make you feel ‘full.’ According to this study, by taking low doses of a probiotic supplement, you may lose up to 8.5% belly fat for just 12 weeks. This is not much, but probiotic supplements are not here to do miracles overnight.

Not all supplement studies have shown that these products are effective. Back in 2018, one study showed that some users didn’t benefit. For example, if you already have a high level of probiotics in your gut, you don’t need to take extra probiotics to replenish your gut health. It means that not all people should use probiotic supplements. If your daily probiotic intake is enough, additional supplements won’t affect your gut health.

Overall, the best probiotic products on Earth are backed by science-proven research and can support your digestive health in multiple ways.

FAQs about Probiotic Supplements

Our team of experts gets plenty of questions about supplements and how they work, and it’s only logical to be interred in something that’s supposed to make your body work better. Here are some of the most frequently asked questions regarding probiotics supplements:

Q: Who should take probiotics?

A: People take probiotics for various reasons. This includes digestive health, energy, immunity, bloating, and weight loss.

Q: What are probiotics?

A: Probiotics are live bacteria beneficial for your body and play a key role in your digestive tract.

Q: Can I use probiotic supplements to lose weight?

A: Yes, you can. Probiotic supplements are proven to enhance the process of weight loss in many consumers. If you struggle to lose weight, you might have a poor probiotic balance, which can be fixed by consuming a probiotic supplement.

Q: What are CFUs?

A: CFUs are colony-forming units, and it’s the strength of the probiotic supplement. The more colonies the supplement has, the more live cultures will enter your body with each serving. On the other hand, more CFUS does not mean that the product is the most effective one on the market, and it doesn’t make it a good supplement.

Q: Will I experience gas if I take probiotic supplements?

A: Some people have experienced bloating or gas right after the first days of taking probiotic supplements. However, you shouldn’t experience gasses beyond the first couple of days of supplementation.

Q: How to take probiotics?

A: Most probiotic supplements are in the form of capsules designed to pass through the stomach’s acid, which means more living bacteria can survive in the digestive tract. However, some probiotics are powdered and in liquid forms.

Q: What is the best probiotic?

A: There is no clear answer, but some products are deemed the best. These products are BioFit, BioTrust Pro-X10, BiOptimizers P30M, and 1MD Complete Probiotics, to name a few.

Q: How are prebiotics and probiotics different?

A: All beneficial, good bacteria in your body are probiotics. On the other side, prebiotics is the ingredients used to feed that bacteria.

Q: Are probiotic supplements beneficial for me?

A: Yes, they are. Probiotic supplements appear to help digestive health and overall health in many different manners. Many studies have confirmed that consuming probiotic supplements can replenish gut bacteria, help you with weight loss, and boost immunity, among various other benefits.

Q: Are probiotics safe?

A: Yes, they are. Probiotics are safe and healthy for adults if taken in regular doses. However, should you cross the line and take substantial dosages without any guidance from a doctor, you might experience a few issues.

Q: Will probiotics help me with bloating?

A: Yes, they will. Although some consumers experience bloating in the first few days, it will all calm down eventually. In this situation, the supplements can help you with bloating while balancing the gut bacteria in your system.

Q: What is the Best Food for Probiotics?

A: The best food with the highest probiotics is kefir, pickles, certain cheeses, tempeh, kimchi, yogurt, and others.

Q: Will I be constipated after taking probiotics?

A: They shouldn’t cause constipation on their own. If you experience this while consuming probiotics, drinking more water, or eating more fiber, it will normalize before you know it.

Q: How fast do prebiotic supplements work?

A: In practice, probiotics work best over two to three weeks. It will take some time to restore and replenish the gut bacteria. If you take probiotic supplements daily for a couple of months, you will have the best chance of reviving the gut bacteria.

The Top Probiotic Supplements for 2022 Final Verdict

To summarize it all up, probiotic supplements are popular and proven ways of supporting gut health. Today, hundreds of manufacturers have worked on various formulas to create the best product. Some products are not as effective as others, so read our list before choosing a product.

By supporting gut health, you will also support weight loss, digestion, allergy defense, immunity, nutrition absorption, and various other features of wellness and health overall.

To read and learn more about probiotics and how they work, or even how to buy one, check the list of the best probiotic supplements on the market today, and pick the one that suits you best!

RELATED:Best Weight Loss Pills: Top Weight Loss Supplements That Work

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

The news and editorial staff of Sound Publishing, Inc. had no role in the preparation of this post. The views and opinions expressed in this sponsored post are those of the advertiser and do not reflect those of Sound Publishing, Inc.

Sound Publishing, Inc. does not accept liability for any loss or damages caused by the use of any products, nor do we endorse any products posted in our Marketplace.

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