It’s “O Brother Where Art Thou?” week in Seattle, with Lucinda Williams, Kathleen Edwards, Carlene Carter and Old Crow Medicine Show all bringing twangy goodness to town. None of them played on the 2000 soundtrack that reintroduced alt-country to millions, but they’ve all benefited from the commercial wave it produced. The twangiest, nasallyest, hootenannyest of them all might be Old Crow Medicine Show, a troupe of acoustic merrymakers from North Carolina by way of New York and southern Indiana. With fiddles, slide guitars, guitjos, and upright bass, the five-piece band works a staggering number of drug references (“Huff paint, cocaine, playing chicken with a train/Smack dab, meth lab, mellow-out, rehab”) into songs of lonely highways, lost loves, and long nights hitchhiking to Raleigh. After two albums produced by producer David Rawlings (Gillian Welch’s musical and life partner and a songwriting genius), the band worked with Don Was on September’s “Tennessee Pusher.” Fortunately, the stripped-down musical formula hasn’t changed much—it goes down as sharp and smooth as the band’s namesake bourbon.

Thu., Nov. 13, 8 p.m., 2008